A 16-year-old patient presents with fatigue, a sore throat, and swollen lymph nodes. The provider suspects infectious mononucleosis and orders a diagnostic test. Which of the following tests is MOST likely to confirm the provider's clinical suspicion?
The Monospot test (Heterophile antibody test) is commonly utilized for the rapid diagnosis of infectious mononucleosis, a condition often caused by the Epstein-Barr virus (EBV). The test detects heterophile antibodies produced by the immune system in response to the infection. This test is chosen due to its quick turnaround time and relatively high specificity and sensitivity during the acute phase of the disease. Other laboratory tests, such as the CBC and throat culture, are not specific to mononucleosis but may be performed to assess overall health or rule out other conditions such as strep throat.
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