The correct answer is counseling the client to avoid combining these two substances due to the potential for dangerous interactions. St. John’s Wort can interact with selective serotonin reuptake inhibitors (SSRIs) such as sertraline, potentially causing serotonin syndrome, a potentially life-threatening condition characterized by symptoms such as confusion, agitation, tremors, and increased heart rate. Educating the client on contraindications ensures their safety. Incorrect options fail to address this critical interaction or provide unsafe advice.
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